Ubiquitylation of an Internalized Killer Cell
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چکیده
منابع مشابه
Ubiquitylation of the chemokine receptor CCR7 enables efficient receptor recycling and cell migration.
The chemokine receptor CCR7 is essential for lymphocyte and dendritic cell homing to secondary lymphoid organs. Owing to the ability to induce directional migration, CCR7 and its ligands CCL19 and CCL21 are pivotal for the regulation of the immune system. Here, we identify a novel function for receptor ubiquitylation in the regulation of the trafficking process of this G-protein-coupled seven t...
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